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Evidence linking oxidative stress, mitochondrial dysfunction, and inflammation in the brain of individuals with autism
D.A. Rossignol and R.E. Frye

Autism spectrum disorders (ASDs) are a heterogeneous group of neurodevelopmental disorders that are defined solely on the basis of behavioral observations. Therefore, ASD has traditionally been framed as a behavioral disorder. However, evidence is accumulating that ASD is characterized by certain physiological abnormalities, including oxidative stress, mitochondrial dysfunction and immune dysregulation/inflammation. 

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