Calhoun, Ari, Naturopathic Doctor

Dr. Ari Calhoun is a Naturopathic Doctor specializing in pediatric neurodevelopment and neuropsychiatric conditions, including autism spectrum disorder, ADHD, PANS/PANDAS, anxiety, depression, Tourette’s, and behavioral and learning disorders. Her work integrates biomedical, genetic, and neuroimmune frameworks to uncover root causes and restore healthy brain function from the womb onward.

Dr. Calhoun is the founder of Wholesome Brain Medicine, a leading clinic in San Diego dedicated to the biomedical treatment of complex neurodevelopmental and behavioral conditions. Her approach bridges functional medicine, genomics, and developmental neuroscience to create individualized treatment plans that address inflammation, mitochondrial health, neurotransmitter balance, and gut-brain-immune regulation.

In addition to her pediatric work, Dr. Calhoun supports women through preconception and pregnancy to optimize fetal brain development, helping families lay the foundation for lifelong cognitive and emotional health.

She is known for her evidence-based, compassionate approach that empowers parents with clarity, strategy, and hope.

• Comprehensive Biomedical Evaluations for autism, ADHD, PANS/PANDAS, anxiety, depression, Tourette’s, and learning or behavioral disorders
• Genetic and Epigenetic Analysis (including methylation, detoxification, neurotransmitter, and immune-related SNPs)
• Functional Lab Testing (gut microbiome, organic acids, immune and inflammatory markers, mitochondrial function, nutrient status, environmental toxin exposure)
• Individualized Treatment Planning integrating nutritional, herbal, nutraceutical, and pharmaceutical interventions
• Detoxification and Mitochondrial Support Protocols for children with immune, metabolic, or toxicant-related vulnerabilities
• Microbiome Restoration and Gut-Brain Axis Optimization
• Neuroinflammation and Immune Regulation Programs for PANS/PANDAS and post-infectious neuropsychiatric syndromes
• Hormone and Adrenal Function Assessment in children and adolescents with chronic stress or neuroendocrine imbalance
• Preconception and Pregnancy Optimization focused on fetal brain development, maternal immune health, and toxin reduction
• Infant and Early Childhood Preventive Care emphasizing microbiome establishment, nutrition, and neurodevelopmental milestones
• Parent and Caregiver Education on environmental and nutritional strategies to reduce neurodevelopmental risk
• Collaborative Care with pediatricians, therapists, neuropsychologists, and other specialists for integrated treatment outcomes

Type of Clients: Both

Take Healthcare Insurance: No

Percentage of ASD children in our practice: 75%

• Autism
• ADHD
• Anxiety
• Apraxia
• Autoimmunity
• Developmental Delays
• Depression
• Disruptive Mood Dysregulation Disorder
• Insomnia
• Eczema
• Oppositional Defiant Disorder
• PANS/PANDAS
• Speech Delay
• Tics and Tourette's Syndrome

Wholesome Brain Medicine offers in person and virtual services to clients within California and beyond. As a practice, we focus on the individual rather than the label. Our goal is to improve quality of life by treating the underlying cause of the presenting symptoms. Regardless of the age, we believe healing is possible. To learn more about our consulting options and determine if we take clients from your state, please visit our website www.wholesomebrainmedicine.com !